Set in an ancient Yoruba kingdom, Orisa follows the story of a powerful but rogue king who rules his people with an iron fist, alienating his chiefs and subjects alike. His reign faces a catastrophic threat when a ruthless gang of bandits, led by a fierce commander, infiltrates the kingdom to kidnap citizens and steal their treasures. Stricken with a mysterious insanity sent by the gods as punishment for his arrogance, the king must lose his mind to find his soul, redeem himself, and team up with his estranged chiefs to save his kingdom from total destruction.